According to findings published in Rheumatologia, the
official journal of the Institute of Rheumatology and the Polish
Rheumatological Society, a daily dose of 1.2 grams of a green lipped mussel (Perna
canaliculus) produced 'significantly less pain, greater joint mobility and no
side effects' in all 25 people taking the supplements for 12 weeks.
In
comparison, a daily dose of 1.2 grams of fish oil, containing 18% EPA and 12%
DHA, produced 'pain relief or increased joint mobility', report researchers
from the Academic Clinical Hospital in Wroclaw, Poland. This study used the
commercial green lipped mussel extract Lyprinol from Pharmalink International,
and the study was partly financed by the company.
"Given the potential side effects, large dosages needed and
long duration required for fish oil, practitioners could consider stabilised Perna
canaliculus oil as a safer and faster acting first-line medication for patients
who suffer from osteoarthritis," wrote the researchers.
Eco-mussel
The NZ green lipped mussel, ranked among the
top 'eco-friendly seafoods' according to the US environmental agency Blue Ocean
Institute's list, is already used as a source of nutraceuticals. The extract, a
rich source of iron, betain, and glycoaminoglycans (including chondroitin
sulphate) has gained a reputation amongst consumers as a natural product with
anti-inflammatory properties - an effect that has been attributed to a body of
science to its lipid factions. The majority of green-lipped mussel extracts reportedly
retain, to a greater or lesser degree of standardisation, the mussels' natural
nutrient profile.
The study
The Polish researchers divided 50 people
into two equal groups. One received eight capsules per day of Lyprinol (150
milligrams per capsule) or eight fish oil capsules per day (150 milligrams per
capsule) for 12 weeks. The authors of the study reported that all 25 of the
subjects who used the mussel oil extract reported significantly less pain,
greater joint mobility and no side effects.
The half of the group who were treated with fish oil
reported no pain relief or increased joint mobility and 36% reported unpleasant
side effects. “In the present study, we observed a surprisingly rapid reduction
of clinical symptoms associated with osteoarthritis notable within four weeks
and continuous improvement over the 12 weeks of the study,” wrote the
researchers.
Source: Rheumatologia Volume 49, Issue 4, Pages 244-252 “Measurement of pain relief resulting from the administration of Perna canaliculus lipid complex PCSO-524 as compared to fish oil for treating patients who suffer from osteoarthritis of knee and/or hip joints”
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